Consumer S Guide To Jak Inhibitors For Ankylosing Spondylitis

NSAIDs, such as ibuprofen or COX-2 inhibitors, which are often used to treat symptoms in milder cases of ankylosing spondylitisBiologics, such as TNF inhibitors or IL-17 inhibitors, which are typically prescribed first to manage moderate to severe ankylosing spondylitis and prevent disease progression

For now, JAK inhibitors are third in line for treating ankylosing spondylitis. That said, “Treatment guidelines were developed before any JAK inhibitors were approved,” explains Dubreuil. The guidelines, developed by the American College of Rheumatology with the Spondylitis Association of America and Spondyloarthritis Research and Treatment Network, were released in 2015. “They haven’t yet incorporated the JAK inhibitor data,” says Dubreuil. “It may be that in the coming years, these drugs come a little earlier in that treatment algorithm, especially as we get more data in regards to adverse events or safety.” Take some extra time to absorb all of this information and decide if JAK inhibitors are something you might want to consider.